Molecular basis for reduced neuraminidase inhibitors susceptibility in highly pathogenic avian influenza A (H5N1) viruses: Perspective on refining antiviral strategies and enhancing pandemic preparedness

Molecular basis for reduced neuraminidase inhibitors susceptibility in highly pathogenic avian influenza A (H5N1) viruses: Perspective on refining antiviral strategies and enhancing pandemic preparedness

The increasing resistance cases in influenza A viruses (IAVs) to different classes of antiviral drugs, necessitates for a detailed investigation of molecular interactions governing reduced susceptibility to these drugs. This study explores the molecular basis of the Highly Pathogenic Avian Influenza...

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Main Authors: Naveen Kumar, Richa Sood, Chhedi Lal Gupta, Ashutosh Singh, Sandeep Bhatia, Manoj Kumar, Shanmuga Nagarajan, Chakradhar Tosh, Harshad Vinayakrao Murugkar, Aniket Sanyal
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:The Microbe
Subjects:
Influenza A viruses
H5N1
Neuraminidase inhibitors
Resistance
Molecular interactions
Online Access:http://www.sciencedirect.com/science/article/pii/S2950194625000512
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