Extraskeletal Myxoid Chondrosarcoma with Small Bowel Metastasis Causing Bowel Obstruction
A 28-year-old female with history of chest wall extraskeletal myxoid chondrosarcoma (EMC) presented to the emergency department complaining of two weeks of lightheadedness and fatigue. Laboratories showed hemoglobin of 7.6 g/dL and a positive hemoccult test. Upper and lower endoscopies were unremark...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | Case Reports in Oncological Medicine |
| Online Access: | http://dx.doi.org/10.1155/2012/621025 |
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| author | Ernesto Bustinza-Linares Francisco Socola Vinicius Ernani Shelly A. Miller Jonathan C. Trent |
| author_facet | Ernesto Bustinza-Linares Francisco Socola Vinicius Ernani Shelly A. Miller Jonathan C. Trent |
| author_sort | Ernesto Bustinza-Linares |
| collection | DOAJ |
| description | A 28-year-old female with history of chest wall extraskeletal myxoid chondrosarcoma (EMC) presented to the emergency department complaining of two weeks of lightheadedness and fatigue. Laboratories showed hemoglobin of 7.6 g/dL and a positive hemoccult test. Upper and lower endoscopies were unremarkable, and the patient was discharged after blood transfusion. The next day she returned to the ED with left-sided weakness and perioral numbness. Brain CT scan revealed a 6 cm right frontal mass with midline shift and edema that required urgent craniotomy with resection of a hemorrhagic tumor. The patient continued dropping her hemoglobin, and CT scans showed a rounded 3 cm small bowel mass in the mid ileum. Repeat upper endoscopy revealed a 2 × 2 cm ulcerated mass in the fourth portion of the duodenum. The patient was taken to the operating room and was found to have two lesions; one in the distal duodenum and a second one in the mid ileum causing small bowel intussusception. Pathology was consistent with metastatic EMC grade 2/3, involving the bowel and mesenteric fat. Extraskeletal myxoid chondrosarcoma (EMC) is a rare soft-tissue sarcoma with unique features that distinguishes, it from other sarcomas. It has been often described as a low-grade sarcoma although there are certain characteristics like high mitotic activity and the presence of focal regions of Ki67 staining above 25% that correlate with aggressive behavior of the tumor. This is the first case of EMC metastatic to the small bowel to be reported to the medical community. |
| format | Article |
| id | doaj-art-7dd94d8c981a4bbeb4e8c024710054e3 |
| institution | Kabale University |
| issn | 2090-6706 2090-6714 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Oncological Medicine |
| spelling | doaj-art-7dd94d8c981a4bbeb4e8c024710054e32025-02-03T01:12:04ZengWileyCase Reports in Oncological Medicine2090-67062090-67142012-01-01201210.1155/2012/621025621025Extraskeletal Myxoid Chondrosarcoma with Small Bowel Metastasis Causing Bowel ObstructionErnesto Bustinza-Linares0Francisco Socola1Vinicius Ernani2Shelly A. Miller3Jonathan C. Trent4Division of Hematology and Oncology, Department of Medicine, Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL 33136, USADivision of Internal Medicine, Department of Medicine, Miller School of Medicine, University of Miami, Miami, FL 33136, USADivision of Internal Medicine, Department of Medicine, Miller School of Medicine, University of Miami, Miami, FL 33136, USADivision of Internal Medicine, Department of Medicine, Miller School of Medicine, University of Miami, Miami, FL 33136, USADivision of Internal Medicine, Department of Medicine, Miller School of Medicine, University of Miami, Miami, FL 33136, USAA 28-year-old female with history of chest wall extraskeletal myxoid chondrosarcoma (EMC) presented to the emergency department complaining of two weeks of lightheadedness and fatigue. Laboratories showed hemoglobin of 7.6 g/dL and a positive hemoccult test. Upper and lower endoscopies were unremarkable, and the patient was discharged after blood transfusion. The next day she returned to the ED with left-sided weakness and perioral numbness. Brain CT scan revealed a 6 cm right frontal mass with midline shift and edema that required urgent craniotomy with resection of a hemorrhagic tumor. The patient continued dropping her hemoglobin, and CT scans showed a rounded 3 cm small bowel mass in the mid ileum. Repeat upper endoscopy revealed a 2 × 2 cm ulcerated mass in the fourth portion of the duodenum. The patient was taken to the operating room and was found to have two lesions; one in the distal duodenum and a second one in the mid ileum causing small bowel intussusception. Pathology was consistent with metastatic EMC grade 2/3, involving the bowel and mesenteric fat. Extraskeletal myxoid chondrosarcoma (EMC) is a rare soft-tissue sarcoma with unique features that distinguishes, it from other sarcomas. It has been often described as a low-grade sarcoma although there are certain characteristics like high mitotic activity and the presence of focal regions of Ki67 staining above 25% that correlate with aggressive behavior of the tumor. This is the first case of EMC metastatic to the small bowel to be reported to the medical community.http://dx.doi.org/10.1155/2012/621025 |
| spellingShingle | Ernesto Bustinza-Linares Francisco Socola Vinicius Ernani Shelly A. Miller Jonathan C. Trent Extraskeletal Myxoid Chondrosarcoma with Small Bowel Metastasis Causing Bowel Obstruction Case Reports in Oncological Medicine |
| title | Extraskeletal Myxoid Chondrosarcoma with Small Bowel Metastasis Causing Bowel Obstruction |
| title_full | Extraskeletal Myxoid Chondrosarcoma with Small Bowel Metastasis Causing Bowel Obstruction |
| title_fullStr | Extraskeletal Myxoid Chondrosarcoma with Small Bowel Metastasis Causing Bowel Obstruction |
| title_full_unstemmed | Extraskeletal Myxoid Chondrosarcoma with Small Bowel Metastasis Causing Bowel Obstruction |
| title_short | Extraskeletal Myxoid Chondrosarcoma with Small Bowel Metastasis Causing Bowel Obstruction |
| title_sort | extraskeletal myxoid chondrosarcoma with small bowel metastasis causing bowel obstruction |
| url | http://dx.doi.org/10.1155/2012/621025 |
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