Acclimation of Hairless Spontaneously Hypertensive Rat to Ambient Temperature Attenuates Hypertension-Induced Pro-Arrhythmic Downregulation of Cx43 in the Left Heart Ventricle of Males

Acclimation of Hairless Spontaneously Hypertensive Rat to Ambient Temperature Attenuates Hypertension-Induced Pro-Arrhythmic Downregulation of Cx43 in the Left Heart Ventricle of Males

Objectives: Due to poor treatment adherence and lifestyle-based interventions, chronic hypertension is a dominant risk factor predisposing individuals to heart failure and malignant arrhythmias. We investigated the impact of the postnatal acclimation of hairless SHR to ambient temperature that is, f...

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Main Authors: Katarina Andelova, Matus Sykora, Veronika Farkasova, Tatiana Stankovicova, Barbara Szeiffova Bacova, Vladimir Knezl, Tamara Egan Benova, Michal Pravenec, Narcis Tribulova
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Biomolecules
Subjects:
hairless SHR
males
females
left and right heart ventricle
connexin43
arrhythmias
Online Access:https://www.mdpi.com/2218-273X/14/12/1509
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