The Evolution of Immunosuppressive Therapy in Pig-to-Nonhuman Primate Organ Transplantation

An overview is provided of the evolution of strategies towards xenotransplantation during the past almost 40 years, focusing on advances in gene-editing of the organ-source pigs, pre-transplant treatment of the recipient, immunosuppressive protocols, and adjunctive therapy. Despite initial challenge...

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Bibliographic Details
Main Authors: S. A. Sanatkar, K. Kinoshita, A. Maenaka, H. Hara, D. K. C. Cooper
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Transplant International
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Online Access:https://www.frontierspartnerships.org/articles/10.3389/ti.2024.13942/full
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