Mechanistic insights into adipose-derived stem cells and exosomes in ischemia-reperfusion injury repair: from shared pathways to organ-specific therapeutics

Mechanistic insights into adipose-derived stem cells and exosomes in ischemia-reperfusion injury repair: from shared pathways to organ-specific therapeutics

Ischemia-reperfusion injury (IRI) has become a significant challenge for clinical treatment due to the complex multi-mechanism pathological cascade response, including oxidative stress, inflammatory bursts, and programmed cell death. Adipose-derived stem cells (ADSCs) and their exosomes (ADSCs-exoso...

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Bibliographic Details
Main Authors: Jiaqian Si, Jie Wang, Hao Dai, Tuochen Lv, Songyun Zhao, Wanying Chen, Liqun Li, Siqi Ding, Yucang He
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
adipose-derived stem cells
exosomes
ischemia-reperfusion injury
multimechanism synergy
therapeutic strategy
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2025.1621289/full
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