Metformin Alleviates Fibrosis of Trabecular Meshwork Cells Induced by TGFβ2 Through the Activation of Autophagy

Objective In this study, we investigated the protective effect of Metformin on fibrosis of trabecular meshwork cells induced by TGFβ2. Methods Transformed and primary human trabecular meshwork cells (HTMCs) were treated with TGFβ2 or Metformin alone or combination, western blotting and immunofluores...

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Bibliographic Details
Main Authors: Jing Ren, Pengtao Wu, Mengli Liu, Xuan Zhang, Zilu Guo, Yihan Liu, Rumeng Zhao, Gang Wang, Shichao Duan, Haijun Li
Format: Article
Language:English
Published: SAGE Publishing 2025-05-01
Series:Dose-Response
Online Access:https://doi.org/10.1177/15593258251341598
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