Investigating cochlear cellular dynamics in neurofibromatosis type 2-associated schwannomatosis: a histopathological study

Investigating cochlear cellular dynamics in neurofibromatosis type 2-associated schwannomatosis: a histopathological study

Sensorineural hearing loss (SNHL) is a hallmark symptom in patients with neurofibromatosis type 2-associated schwannomatosis (NF2-SWN), a genetic condition caused by mutations in the Neurofibromin II gene that encodes the tumor suppressor protein Moesin-Ezrin-Radixin-Like Protein (Merlin; also known...

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Bibliographic Details
Main Authors: Reef K. Al-Asad, Drew J. Montigny, Jennifer T. O’Malley, D. Bradley Welling, David H. Jung, Andreas H. Eckhard, Judith S. Kempfle
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Neurology
Subjects:
neurofibromatosis type 2
Schwann cells
macrophages
sensorineural hearing loss
NF2-SWN
spiral ganglion neurons
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2025.1650470/full
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https://www.frontiersin.org/articles/10.3389/fneur.2025.1650470/full

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