Protocol to generate a 3D atherogenesis-on-chip model for studying endothelial-macrophage crosstalk in atherogenesis

Summary: The endothelium is the gatekeeper of vessel health, and its dysfunction is pivotal in driving atherogenesis. Here, we present a protocol to replicate endothelial-macrophage crosstalk during atherogenesis, called the “atherogenesis-on-chip” model, based on the Emulate dual-channel perfusion...

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Bibliographic Details
Main Authors: Katie M.L. Hanford, Kim E. Dzobo, Miranda Versloot, Jorge Peter, Jeffrey Kroon
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:STAR Protocols
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Online Access:http://www.sciencedirect.com/science/article/pii/S266616672400724X
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