Safety and efficacy of osimertinib 160 mg daily given concurrently with a strong CYP3A4 inducer

Introduction: Osimertinib remains the standard first-line therapy for patients with advanced EGFR-mutant NSCLC, at least in part due to its improved CNS penetrance compared to earlier generation EGFR TKIs. Strong CYP3A4-inducing medications are known to reduce the effective concentration of osimerti...

Full description

Saved in:
Bibliographic Details
Main Authors: Mostafa Aglan, Erin Spyropoulous, Joel Oster, Paul J. Hesketh, A.J. Piper-Vallillo
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Respiratory Medicine Case Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S221300712500036X
Tags: Add Tag
No Tags, Be the first to tag this record!