Plasma concentrations of neurofilament light, p-Tau231 and glial fibrillary acidic protein are elevated in patients with chronic kidney disease and correlate with measured glomerular filtration rate

Plasma concentrations of neurofilament light, p-Tau231 and glial fibrillary acidic protein are elevated in patients with chronic kidney disease and correlate with measured glomerular filtration rate

Abstract Background Patients with chronic kidney disease (CKD) have a high prevalence of cerebrovascular disease and cognitive impairment. The objective was to analyse whether plasma concentrations of neurofilament light chain (NfL), glial fibrillary acidic protein (GFAP) and phosphorylated Tau231 (...

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Main Authors: Torunn Axelsson, Henrik Zetterberg, Kaj Blennow, Burak Arslan, Nicholas J. Ashton, Markus Axelsson, Maria K. Svensson, Aso Saeed, Gregor Guron
Format: Article
Language:English
Published: BMC 2025-05-01
Series:BMC Nephrology
Subjects:
Chronic kidney disease
Glial fibrillary acidic protein
Glomerular filtration rate
Neurofilament light
Tau
Online Access:https://doi.org/10.1186/s12882-025-04130-2
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https://doi.org/10.1186/s12882-025-04130-2

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