Statin Induced Changes in Rat Pancreatic Tissue: A Histological and Biochemical Perspective

Statin Induced Changes in Rat Pancreatic Tissue: A Histological and Biochemical Perspective

Objective: This study aimed to elucidate the effects of simvastatin on pancreatic histomorphology and biochemical profile in a rat model. Method: Forty male Sprague-Dawley rats weighing 250 g were divided into two equal groups: a control group (A) and an experimental group (B) treated with simvas...

Full description

Saved in:

Bibliographic Details
Main Authors:	Abdullah Qamar, Hammad Gul Khan, Muhammad Marghoob Khan, Muhammad Rizwan Bashir Kiani, Hina Kundi, Fareeha Mushtaq
Format:	Article
Language:	English
Published:	Rawalpindi Medical University 2024-03-01
Series:	Journal of Rawalpindi Medical College
Online Access:	https://www.journalrmc.com/index.php/JRMC/article/view/2367
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

The Effects Of Simvastatin On Islets Of Langerhans In The Pancreas Of Rats: A Histological And Biochemical Study
by: Abdullah Qamar, et al.
Published: (2024-01-01)

Impact of caffeine and vitamin D3 on the body-weight of pregnant BALB/c mice
by: Maimoona Khan, et al.
Published: (2023-04-01)

Zinc Supplementation Mitigates High Salt Diet-Induced Bone Damage: A Histological Evaluation of Osteocyte Apoptosis
by: Kaukab Anjum, et al.
Published: (2025-01-01)

The effect of local propolis irrigation as an adjunct to scaling and root planning on alveolar bone loss in experimental periodontitis in rats (A biochemical and histological study).
by: Khadeeja Mohammed Ali, et al.
Published: (2022-07-01)

Orally administered organophosphorus dimethoate mediated biochemical alterations in male and female experimental Rattus norvegicus (albino rats)
by: Nida Saleem, et al.
Published: (2025-02-01)

Transcriptomic, histological and biochemical analyses of Macrobrachium nipponense response to acute heat stress
by: Xiao Wu, et al.
Published: (2025-01-01)

Ameliorating Effects of Arsenic-Induced Toxicity On The Histology Of Vagina And Reproductive Hormones Of Female Sprague Dawley Rats
by: Amaidah Mir, et al.
Published: (2024-03-01)

Impact of long-term cyanotoxin exposure on cattle: Biochemical, histological, and oxidative stress assessment
by: Mounira Bensalem, et al.
Published: (2025-01-01)

Hepatic Damage Induced By Fructose And Aspartame In Carbonated Drinks: Morphological And Histological Analysis In Adult Male Albino Rats
by: Faiza Shafqat, et al.
Published: (2024-12-01)

Taurine Prevented Biochemical Alterations in Chronic Restraint-Stressed Wistar Rats
by: Iliya, Ezekiel, et al.
Published: (2023)

Inflammatory Bowel Disease and Statins
by: V. V. Genkel, et al.
Published: (2020-04-01)

Effect of nanoemulsion carbonated hydroxyapatite-statin administration on Acp 5 and Runx-2 expression during orthodontic relapse in rats
by: Ananto Ali Alhasyimi, et al.
Published: (2025-01-01)

When herpes zoster is not herpes: A case of statin-induced myopathy complicated by drug allergies
by: Hira Khalid Kareem, et al.
Published: (2025-01-01)

Targeting the hERG1/β1 integrin complex in lipid rafts potentiates statins anti-cancer activity in pancreatic cancer
by: Claudia Duranti, et al.
Published: (2025-02-01)

Intracardiac Ectopic Thyroid Tissue: A Case Report
by: Hira Nasir, et al.
Published: (2024-09-01)

GWAS of CRP response to statins further supports the role of APOE in statin response: A GIST consortium study
by: Emma F. Magavern, et al.
Published: (2025-02-01)

Effects of Celery Seed Extracts on Some Haematological and Biochemical Parameters in Albino Rats Treated with Gentamicin
by: Tavga Ismael Mustafa, et al.
Published: (2019-08-01)

The clinical utility of tissue polymerase chain reaction, tissue culture and tissue histology in blood culture-negative infective endocarditis in South Africa – insights from the Groote Schuur Hospital Infective Endocarditis Registry
by: W Endres, et al.
Published: (2025-02-01)

The compressive strength development and pH of cement mortars incorporating high volume supplementary cementitious materials under accelerated curing
by: Sumra Yousuf, et al.
Published: (2025-02-01)

Serum High-Density Lipoprotein Cholesterol Concentrations in Pancreatic Ductal Adenocarcinoma and Its Association With Histological Grade in a Chinese Population
by: Ying-Ying Cao PhD, et al.
Published: (2025-01-01)

Concise Histology /
by: Gartner, Leslie P., 1943-
Published: (2011)

An Overview of the Impact of Statin Therapy on Cardiac Incident Risk
by: Urszula Świrk, et al.
Published: (2025-02-01)

Effect of Aloe vera gel on the parotid glands of streptozotocin-induced diabetic albino rats: histological and immunohistochemical study.
by: Shukria Mohammed Hussein
Published: (2022-07-01)

Subacute toxicity of isoliquiritigenin-zein phosphatidylcholine nanoparticles on biochemical, hematological, and histopathological parameters in Sprague-Dawley rats
by: Ke Yang, et al.
Published: (2024-04-01)

Differential Antimicrobial Potential of Ajuga integrifolia Buch. Ham. Ex D.Don Based on Extraction Solvents
by: Wajid Khan, et al.
Published: (2025-01-01)

Cyto-histological correlation of salivary gland lesions according to the Milan reporting system
by: Shireen Hamid, et al.
Published: (2024-09-01)

Histology: color atlas of microscopic anatomy /
by: Hammersen, Frithjof
Published: (1985)

Acute toxicity test of Rhizophora apiculata bark extract on rat liver and kidney histology using fixed dose method
by: Syazili Mustofa, et al.
Published: (2024-07-01)

Color Atlas of Histology /
by: Hiater James L.
Published: (2000)

Color Atlas of Histology /
by: Gartner , Leslie P.
Published: (2000)

Cell Biology and Histology /
by: Gartner, Leslie P
Published: (2007)

Oral Development and Histology /
Published: (1987)

Histology : a text and atlas with cell and molecular biology /
by: Ross ,Micheal H.
Published: (2003)

Prediction of biochemical prostate cancer recurrence from any Gleason score using robust tissue structure and clinically available information
by: Laura E. Marin, et al.
Published: (2025-02-01)

Risk Factors For Progression From Biochemical Leak to Clinically Relevant Postoperative Pancreatic Fistula After Pancreaticoduodenectomy. The Key of the Lock: Prognostic Nutritional Index
by: Mehmet Can Aydin, et al.
Published: (2025-02-01)

The Frequency Of Maternal Near Misses At Benazir Bhutto Hospital- Using The WHO Standard Tool, A Cross-Sectional Study
by: Humaira Masood, et al.
Published: (2024-12-01)

Reparative histogenesis of bone tissue in femoral fractures in rats using biocomposite material along with immunocorrection
by: V. V. Reshetnyak, et al.
Published: (2021-08-01)

Effect of Different Dietary Oils and Fat on Body Weight, Food Intake, Some Haematological and Biochemical Parameters in Female Albino Rats
by: Zerawan Sadiq Abdullah, et al.
Published: (2018-07-01)

Ameliorated Impact of Fenugreek Seed Extract on Some Blood Cellular and Biochemical Parameters in Female Albino Rats Exposed to Lead Acetate
by: Rozhya Abduljalil Naser, et al.
Published: (2020-12-01)

Statin prescriptions and progression of advanced fibrosis risk in primary care patients with MASLD
by: Andrew D Schreiner, et al.
Published: (2024-07-01)