Differential expression of phosphoinositide 3-kinase/protein kinase B and Toll-like receptor/nuclear factor kappa B signaling pathways in experimental obesity Wistar rat model

This study investigated the effects of activation and inhibition of the PI3K/AKT and TLR-4/NF-κB signaling pathways on insulin resistance in a high-fat diet-induced obese rat model. The results indicate that a high-fat diet can activate these signaling pathways by regulating the expression of relate...

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Bibliographic Details
Main Authors: Song Liya, Li Lihua
Format: Article
Language:English
Published: De Gruyter 2024-12-01
Series:Open Life Sciences
Subjects:
Online Access:https://doi.org/10.1515/biol-2022-1014
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