Hemodynamic Factors Driving Peripheral Chemoreceptor Hypersensitivity: Is Severe Aortic Stenosis Treated with Transcatheter Aortic Valve Implantation a Valuable Human Model?

Hemodynamic Factors Driving Peripheral Chemoreceptor Hypersensitivity: Is Severe Aortic Stenosis Treated with Transcatheter Aortic Valve Implantation a Valuable Human Model?

<b>Background:</b> A reduction in carotid artery blood flow (CABF) and ultimately in wall shear stress (WSS) is a major driver of heightened peripheral chemoreceptor (PCh) activity in animal models of heart failure. However, it is yet to be translated to humans. To provide more insight i...

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Bibliographic Details
Main Authors: Maksym Jura, Stanisław Tubek, Jędrzej Reczuch, Rafał Seredyński, Piotr Niewiński, Marcin Protasiewicz, Beata Ponikowska, Bartłomiej Paleczny
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Biomedicines
Subjects:
peripheral chemoreceptors
peripheral chemoreflex
carotid body
aortic body
aortic stenosis
transcatheter aortic valve implantation
Online Access:https://www.mdpi.com/2227-9059/13/3/611
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