Behavioural Problems in Children with 46XY Disorders of Sex Development

The aim of this study is to determine the behavioural problems of children with 46XY disorders of sex development (DSD) with genital ambiguity and to identify the risk factors that may influence behaviour. The 27 participants (aged 6–18 years) consisted of 21 patients raised as boys and 6 patients r...

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Main Authors: Nalini M. Selveindran, Syed Zulkifli Syed Zakaria, Muhammad Yazid Jalaludin, Rahmah Rasat
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:International Journal of Endocrinology
Online Access:http://dx.doi.org/10.1155/2017/5987490
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author Nalini M. Selveindran
Syed Zulkifli Syed Zakaria
Muhammad Yazid Jalaludin
Rahmah Rasat
author_facet Nalini M. Selveindran
Syed Zulkifli Syed Zakaria
Muhammad Yazid Jalaludin
Rahmah Rasat
author_sort Nalini M. Selveindran
collection DOAJ
description The aim of this study is to determine the behavioural problems of children with 46XY disorders of sex development (DSD) with genital ambiguity and to identify the risk factors that may influence behaviour. The 27 participants (aged 6–18 years) consisted of 21 patients raised as boys and 6 patients raised as girls. Control data were obtained from a representative sibling of each patient who was matched for age and gender. The study tool used was the Child Behaviour Checklist (CBCL), which is a parent-administered questionnaire. The analysis of the behavioural scores revealed that the patient group had poorer scores in the total, externalizing, and internalizing realms. This group also had poorer scores in the anxious-depressed, social, and rule-breaking realms as compared to the control group. In addition, the XY-F group had higher scores (more pathological) than the XY-M group, although the difference in the scores was not statistically significant. A comparison of the prevalence of patients with scores in the clinical range with that of the control group was not statistically significant. These findings support the current recommendations that psychological counselling should be an integral part of the professional support offered to patients with DSD.
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institution Kabale University
issn 1687-8337
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language English
publishDate 2017-01-01
publisher Wiley
record_format Article
series International Journal of Endocrinology
spelling doaj-art-7cea6b5753c24e5eab6bfd1bdb9319732025-02-03T05:58:16ZengWileyInternational Journal of Endocrinology1687-83371687-83452017-01-01201710.1155/2017/59874905987490Behavioural Problems in Children with 46XY Disorders of Sex DevelopmentNalini M. Selveindran0Syed Zulkifli Syed Zakaria1Muhammad Yazid Jalaludin2Rahmah Rasat3Department of Paediatrics, Hospital Putrajaya, Pusat Pentadbiran Putrajaya, Presint 7, 62250 Putrajaya, MalaysiaDepartment of Paediatrics, University Kebangsaan Malaysia Medical Centre, Jalan Yaacob Latiff, Bandar Tun Razak Cheras, 56000 Kuala Lumpur, MalaysiaDepartment of Paediatrics, Faculty of Medicine, University Malaya, 59100 Kuala Lumpur, MalaysiaDepartment of Paediatrics, University Kebangsaan Malaysia Medical Centre, Jalan Yaacob Latiff, Bandar Tun Razak Cheras, 56000 Kuala Lumpur, MalaysiaThe aim of this study is to determine the behavioural problems of children with 46XY disorders of sex development (DSD) with genital ambiguity and to identify the risk factors that may influence behaviour. The 27 participants (aged 6–18 years) consisted of 21 patients raised as boys and 6 patients raised as girls. Control data were obtained from a representative sibling of each patient who was matched for age and gender. The study tool used was the Child Behaviour Checklist (CBCL), which is a parent-administered questionnaire. The analysis of the behavioural scores revealed that the patient group had poorer scores in the total, externalizing, and internalizing realms. This group also had poorer scores in the anxious-depressed, social, and rule-breaking realms as compared to the control group. In addition, the XY-F group had higher scores (more pathological) than the XY-M group, although the difference in the scores was not statistically significant. A comparison of the prevalence of patients with scores in the clinical range with that of the control group was not statistically significant. These findings support the current recommendations that psychological counselling should be an integral part of the professional support offered to patients with DSD.http://dx.doi.org/10.1155/2017/5987490
spellingShingle Nalini M. Selveindran
Syed Zulkifli Syed Zakaria
Muhammad Yazid Jalaludin
Rahmah Rasat
Behavioural Problems in Children with 46XY Disorders of Sex Development
International Journal of Endocrinology
title Behavioural Problems in Children with 46XY Disorders of Sex Development
title_full Behavioural Problems in Children with 46XY Disorders of Sex Development
title_fullStr Behavioural Problems in Children with 46XY Disorders of Sex Development
title_full_unstemmed Behavioural Problems in Children with 46XY Disorders of Sex Development
title_short Behavioural Problems in Children with 46XY Disorders of Sex Development
title_sort behavioural problems in children with 46xy disorders of sex development
url http://dx.doi.org/10.1155/2017/5987490
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