Metabolomics Profiling Reveals Critical Roles of Indoxyl Sulfate in the Regulation of Innate Monocytes in COVID-19

Metabolomics Profiling Reveals Critical Roles of Indoxyl Sulfate in the Regulation of Innate Monocytes in COVID-19

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is intricately related to the reprogramming of host metabolism. However, existing studies have mainly focused on peripheral blood samples and barely identified specific metabolites that are critically involved in the patholog...

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Bibliographic Details
Main Authors: Liqing He, Yunke Wang, Fang Yuan, Samantha Morrissey, Anne E. Geller, Xiaoling Hu, Raobo Xu, Xipeng Ma, Huang-ge Zhang, Kenneth McLeish, Jiapeng Huang, Xiang Zhang, Jun Yan
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Cells
Subjects:
COVID-19
metabolism
indoxyl sulfate
monocytes
immune regulation
Online Access:https://www.mdpi.com/2073-4409/14/4/256
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