Get ready for short tandem repeats analysis using long reads-the challenges and the state of the art

Short tandem repeats (STRs) are repetitive DNA sequences that contribute to genetic diversity and play a significant role in disease susceptibility. The human genome contains approximately 1.5 million STR loci, collectively covering around 3% of the total sequence. Certain repeat expansions can sign...

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Bibliographic Details
Main Authors: Marija Chaushevska, Karmele Alapont-Celaya, Anne Kristine Schack, Lukasz Krych, M. Carmen Garrido Navas, Anastasia Krithara, Gjorgji Madjarov
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Genetics
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Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2025.1610026/full
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