Recent Advances in the Recognition and Management of Eosinophilic Esophagitis

The incidence and recognition of eosinophilic esophagitis is increasing. Pathophysiological understanding of eosinophilic esophagitis is improving and an immunological reaction to ingested food is likely to play a significant role. Patients present with dysphagia and food bolus obstruction. Both his...

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Main Authors: Gregory Eustace, Xianyong Gui, Marietta Iacucci
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Canadian Journal of Gastroenterology and Hepatology
Online Access:http://dx.doi.org/10.1155/2015/403108
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author Gregory Eustace
Xianyong Gui
Marietta Iacucci
author_facet Gregory Eustace
Xianyong Gui
Marietta Iacucci
author_sort Gregory Eustace
collection DOAJ
description The incidence and recognition of eosinophilic esophagitis is increasing. Pathophysiological understanding of eosinophilic esophagitis is improving and an immunological reaction to ingested food is likely to play a significant role. Patients present with dysphagia and food bolus obstruction. Both histological and endoscopic criteria have been developed and validated. Dietary therapy, topical steroid therapy, proton pump inhibitors and endoscopic dilation are the main approaches to therapy; however, novel targeted therapies are being developed. Among the food items commonly implicated are wheat, dairy, nuts, soy, shellfish and eggs. A multidisciplinary approach to management in dedicated clinics may yield the best results.
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institution Kabale University
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series Canadian Journal of Gastroenterology and Hepatology
spelling doaj-art-7c889763d1b84db3b00b25a5df69b2982025-02-03T01:03:10ZengWileyCanadian Journal of Gastroenterology and Hepatology2291-27892291-27972015-01-0129523724010.1155/2015/403108Recent Advances in the Recognition and Management of Eosinophilic EsophagitisGregory Eustace0Xianyong Gui1Marietta Iacucci2Division of Gastroenterology, Department of Medicine, University of Calgary, Calgary, Alberta, CanadaDivision of Gastroenterology, Department of Medicine, University of Calgary, Calgary, Alberta, CanadaDivision of Gastroenterology, Department of Medicine, University of Calgary, Calgary, Alberta, CanadaThe incidence and recognition of eosinophilic esophagitis is increasing. Pathophysiological understanding of eosinophilic esophagitis is improving and an immunological reaction to ingested food is likely to play a significant role. Patients present with dysphagia and food bolus obstruction. Both histological and endoscopic criteria have been developed and validated. Dietary therapy, topical steroid therapy, proton pump inhibitors and endoscopic dilation are the main approaches to therapy; however, novel targeted therapies are being developed. Among the food items commonly implicated are wheat, dairy, nuts, soy, shellfish and eggs. A multidisciplinary approach to management in dedicated clinics may yield the best results.http://dx.doi.org/10.1155/2015/403108
spellingShingle Gregory Eustace
Xianyong Gui
Marietta Iacucci
Recent Advances in the Recognition and Management of Eosinophilic Esophagitis
Canadian Journal of Gastroenterology and Hepatology
title Recent Advances in the Recognition and Management of Eosinophilic Esophagitis
title_full Recent Advances in the Recognition and Management of Eosinophilic Esophagitis
title_fullStr Recent Advances in the Recognition and Management of Eosinophilic Esophagitis
title_full_unstemmed Recent Advances in the Recognition and Management of Eosinophilic Esophagitis
title_short Recent Advances in the Recognition and Management of Eosinophilic Esophagitis
title_sort recent advances in the recognition and management of eosinophilic esophagitis
url http://dx.doi.org/10.1155/2015/403108
work_keys_str_mv AT gregoryeustace recentadvancesintherecognitionandmanagementofeosinophilicesophagitis
AT xianyonggui recentadvancesintherecognitionandmanagementofeosinophilicesophagitis
AT mariettaiacucci recentadvancesintherecognitionandmanagementofeosinophilicesophagitis