Recent Advances in the Recognition and Management of Eosinophilic Esophagitis
The incidence and recognition of eosinophilic esophagitis is increasing. Pathophysiological understanding of eosinophilic esophagitis is improving and an immunological reaction to ingested food is likely to play a significant role. Patients present with dysphagia and food bolus obstruction. Both his...
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Format: | Article |
Language: | English |
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Wiley
2015-01-01
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Series: | Canadian Journal of Gastroenterology and Hepatology |
Online Access: | http://dx.doi.org/10.1155/2015/403108 |
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author | Gregory Eustace Xianyong Gui Marietta Iacucci |
author_facet | Gregory Eustace Xianyong Gui Marietta Iacucci |
author_sort | Gregory Eustace |
collection | DOAJ |
description | The incidence and recognition of eosinophilic esophagitis is increasing. Pathophysiological understanding of eosinophilic esophagitis is improving and an immunological reaction to ingested food is likely to play a significant role. Patients present with dysphagia and food bolus obstruction. Both histological and endoscopic criteria have been developed and validated. Dietary therapy, topical steroid therapy, proton pump inhibitors and endoscopic dilation are the main approaches to therapy; however, novel targeted therapies are being developed. Among the food items commonly implicated are wheat, dairy, nuts, soy, shellfish and eggs. A multidisciplinary approach to management in dedicated clinics may yield the best results. |
format | Article |
id | doaj-art-7c889763d1b84db3b00b25a5df69b298 |
institution | Kabale University |
issn | 2291-2789 2291-2797 |
language | English |
publishDate | 2015-01-01 |
publisher | Wiley |
record_format | Article |
series | Canadian Journal of Gastroenterology and Hepatology |
spelling | doaj-art-7c889763d1b84db3b00b25a5df69b2982025-02-03T01:03:10ZengWileyCanadian Journal of Gastroenterology and Hepatology2291-27892291-27972015-01-0129523724010.1155/2015/403108Recent Advances in the Recognition and Management of Eosinophilic EsophagitisGregory Eustace0Xianyong Gui1Marietta Iacucci2Division of Gastroenterology, Department of Medicine, University of Calgary, Calgary, Alberta, CanadaDivision of Gastroenterology, Department of Medicine, University of Calgary, Calgary, Alberta, CanadaDivision of Gastroenterology, Department of Medicine, University of Calgary, Calgary, Alberta, CanadaThe incidence and recognition of eosinophilic esophagitis is increasing. Pathophysiological understanding of eosinophilic esophagitis is improving and an immunological reaction to ingested food is likely to play a significant role. Patients present with dysphagia and food bolus obstruction. Both histological and endoscopic criteria have been developed and validated. Dietary therapy, topical steroid therapy, proton pump inhibitors and endoscopic dilation are the main approaches to therapy; however, novel targeted therapies are being developed. Among the food items commonly implicated are wheat, dairy, nuts, soy, shellfish and eggs. A multidisciplinary approach to management in dedicated clinics may yield the best results.http://dx.doi.org/10.1155/2015/403108 |
spellingShingle | Gregory Eustace Xianyong Gui Marietta Iacucci Recent Advances in the Recognition and Management of Eosinophilic Esophagitis Canadian Journal of Gastroenterology and Hepatology |
title | Recent Advances in the Recognition and Management of Eosinophilic Esophagitis |
title_full | Recent Advances in the Recognition and Management of Eosinophilic Esophagitis |
title_fullStr | Recent Advances in the Recognition and Management of Eosinophilic Esophagitis |
title_full_unstemmed | Recent Advances in the Recognition and Management of Eosinophilic Esophagitis |
title_short | Recent Advances in the Recognition and Management of Eosinophilic Esophagitis |
title_sort | recent advances in the recognition and management of eosinophilic esophagitis |
url | http://dx.doi.org/10.1155/2015/403108 |
work_keys_str_mv | AT gregoryeustace recentadvancesintherecognitionandmanagementofeosinophilicesophagitis AT xianyonggui recentadvancesintherecognitionandmanagementofeosinophilicesophagitis AT mariettaiacucci recentadvancesintherecognitionandmanagementofeosinophilicesophagitis |