Reprogramming FGF1 from the natural growth factor to the engineered heparan sulphate biosensor

Abstract Heparan sulphate proteoglycans (HSPGs) are cell surface and extracellular matrix proteoglycan family members, playing a key role in diverse biological activities including signal transduction or endocytosis. To date, many HSPG ligands have been identified, including growth factors interacti...

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Bibliographic Details
Main Authors: Krzysztof Ciura, Olimpia Sobota, Aleksandra Chorążewska, Daniel Krowarsch, Natalia Porębska, Łukasz Opaliński
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Cell Communication and Signaling
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Online Access:https://doi.org/10.1186/s12964-025-02269-x
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