Re-Examination of the Sel’kov Model of Glycolysis and Its Symmetry-Breaking Instability Due to the Impact of Diffusion with Implications for Cancer Imitation Caused by the Warburg Effect

Re-Examination of the Sel’kov Model of Glycolysis and Its Symmetry-Breaking Instability Due to the Impact of Diffusion with Implications for Cancer Imitation Caused by the Warburg Effect

We revisit the seminal model of glycolysis first proposed by Sel’kov more than fifty years ago. We investigate the onset of instabilities in biological systems described by the Sel’kov model in order to determine the conditions of the model parameters that lead to bifurcations. We analyze the glycol...

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Bibliographic Details
Main Authors: Miljko V. Satarić, Tomas Nemeš, Jack A. Tuszynski
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Biophysica
Subjects:
glycolysis
ATP
ADP
diffusion
symmetry-breaking instability
Online Access:https://www.mdpi.com/2673-4125/4/4/36
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