Modelling reveals novel roles of two parallel signalling pathways and homeostatic feedbacks in yeast

Abstract The high osmolarity glycerol (HOG) pathway in yeast serves as a prototype signalling system for eukaryotes. We used an unprecedented amount of data to parameterise 192 models capturing different hypotheses about molecular mechanisms underlying osmo‐adaptation and selected a best approximati...

Full description

Saved in:
Bibliographic Details
Main Authors: Jörg Schaber, Rodrigo Baltanas, Alan Bush, Edda Klipp, Alejandro Colman‐Lerner
Format: Article
Language:English
Published: Springer Nature 2012-11-01
Series:Molecular Systems Biology
Subjects:
Online Access:https://doi.org/10.1038/msb.2012.53
Tags: Add Tag
No Tags, Be the first to tag this record!