Frontal cortex hyperactivation and gamma desynchrony in Fragile X syndrome: Correlates of auditory hypersensitivity.

Fragile X syndrome (FXS) is an X-linked disorder that often leads to intellectual disability, anxiety, and sensory hypersensitivity. While sound sensitivity (hyperacusis) is a distressing symptom in FXS, its neural basis is not well understood. It is postulated that hyperacusis may stem from tempora...

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Main Authors: Ernest V Pedapati, Lauren E Ethridge, Yanchen Liu, Rui Liu, John A Sweeney, Lisa A DeStefano, Makoto Miyakoshi, Khaleel Razak, Lauren M Schmitt, David R Moore, Donald L Gilbert, Steve W Wu, Elizabeth Smith, Rebecca C Shaffer, Kelli C Dominick, Paul S Horn, Devin Binder, Craig A Erickson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0306157
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