Curcumin modulates β-catenin stabilization via targeting proteasomal deubiquitinating enzyme USP14☆

Loss of β-catenin homeostasis is tightly associated with human malignancies, modulation of β-catenin stabilization could be an attractive strategy for cancer therapy. In the present study, we demonstrated that an ancient drug curcumin was associated with selective accumulation of phosphorylated β-ca...

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Bibliographic Details
Main Authors: Mengzhen Shen, Lizhe Chen, Jie Jiang, Ziye Wang, Qing Gong, Xue Zhang, Xisong Ke, Yi Qu
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Pharmacological Research
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Online Access:http://www.sciencedirect.com/science/article/pii/S1043661825001707
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