The role of DPP6 dysregulation in neuropathology: from synaptic regulation to disease mechanisms

As a transmembrane protein, DPP6 modulates the function and properties of ion channels, playing a crucial role in various tissues, particularly in the brain. DPP6 interacts with potassium channel Kv4.2 (KCND2), enhancing its membrane expression and channel kinetics. Potassium ion channels are critic...

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Bibliographic Details
Main Authors: Xuan-Yan Ding, Jean de Dieu Habimana, Zhi-Yuan Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Cellular Neuroscience
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Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2025.1547495/full
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