Polymorphism in LEP and LEPR May Modify Leptin Levels and Represent Risk Factors for Thyroid Cancer

Polymorphism in LEP and LEPR May Modify Leptin Levels and Represent Risk Factors for Thyroid Cancer

Purpose. To understand the role of polymorphisms in the LEP (rs7799039 and rs2167270) and LEPR (rs1137101 and rs1137100) genes in DTC susceptibility and their effect on leptin levels. Methods. We studied 153 patients with DTC and 234 controls through TaqMan SNP Genotyping and ELISA, comparing these...

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Main Authors: Marjory Alana Marcello, Antonio Ramos Calixto, Jacqueline Fatima Martins de Almeida, Mariana Bonjiorno Martins, Lucas Leite Cunha, Camila Ayume Amano Cavalari, Elba C. S. Etchebehere, Ligia Vera Montalli da Assumpção, Bruno Geloneze, Andre Lopes Carvalho, Laura Sterian Ward
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:International Journal of Endocrinology
Online Access:http://dx.doi.org/10.1155/2015/173218
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http://dx.doi.org/10.1155/2015/173218

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