Akkermansia muciniphila reverses neuronal atrophy in Negr1 knockout mice with depression-like phenotypes

Akkermansia muciniphila reverses neuronal atrophy in Negr1 knockout mice with depression-like phenotypes

Genetic predispositions can shape the gut microbiome, which in turn modulates host gene expression and impacts host physiology. The complex interplay between host genetics and the gut microbiome likely contributes to the development of neuropsychiatric disorders, yet the mechanisms behind these inte...

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Main Authors: Hee-Gon Hwang, Ji-Woo Park, Hyo-Jin Lee, Moon Yi Ko, Minhan Ka, Yun Kyung Lee, Jaeyoon Choi, Su-A In, Ye-Eun Lee, Soojin Lee, Min-Soo Kim, Jeong-Yoon Kim
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Gut Microbes
Subjects:
Akkermansia muciniphila
genetic predisposition
microbiome
depression
Online Access:https://www.tandfonline.com/doi/10.1080/19490976.2025.2508424
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https://www.tandfonline.com/doi/10.1080/19490976.2025.2508424

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