The 8-bromobaicalein alleviated chikungunya-induced musculoskeletal inflammation and reduced the viral load in healthy adult mice

The 8-bromobaicalein alleviated chikungunya-induced musculoskeletal inflammation and reduced the viral load in healthy adult mice

Chikungunya virus is a re-emerging arbovirus that has caused epidemic outbreaks in recent decades. Patients in older age groups with high viral load and severe immunologic response during acute infection are likely to develop chronic arthritis and severe joint pain. Currently, no antiviral drug is a...

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Main Authors: Van Cao, Naphat Loeanurit, Kowit Hengphasatporn, Rita Hairani, Noppadol Wacharachaisurapol, Nantaporn Prompila, Supeecha Wittayalertpanya, Yasuteru Shigeta, Tanatorn Khotavivattana, Warinthorn Chavasiri, Siwaporn Boonyasuppayakorn
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Emerging Microbes and Infections
Subjects:
Drug discovery
8-bromobaicalein
chikungunya virus
flavone derivatives
flavonoid
in vivo efficacy
Online Access:https://www.tandfonline.com/doi/10.1080/22221751.2023.2270074
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https://www.tandfonline.com/doi/10.1080/22221751.2023.2270074

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