DFO-loaded PDA nanoparticles facilitated 3D stem cell spheroids for diabetic wound repair by normalizing the pathological microenvironment

DFO-loaded PDA nanoparticles facilitated 3D stem cell spheroids for diabetic wound repair by normalizing the pathological microenvironment

Diabetic wounds represent a prevalent and challenging complication of diabetes, characterized by compromised immune function, chronic inflammation, oxidative stress, and impaired revascularization, all of which impede normal wound healing. Despite the high therapeutic potential of 3D stem cell spher...

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Main Authors: Tong Luo, Peijun Zhu, Shuai Li, Maolin Qin, Zeyu Fang, Fangfang Wu, Qian Wu, Suhong Lu, Yinhe Zhang, Yuli Chen, Junhua Zhou, Daqing Chen, Liangliang Yang, Hongyu Zhang
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:Materials Today Bio
Subjects:
Stem cell spheroids
Polydopamine nanoparticles
DFO
Hydrogel
Diabetic wound
Online Access:http://www.sciencedirect.com/science/article/pii/S2590006425005435
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