Neutrophil adhesion to vessel walls impairs pulmonary circulation in COVID-19 pathology

Neutrophil adhesion to vessel walls impairs pulmonary circulation in COVID-19 pathology

Abstract Microthrombus formation is associated with COVID-19 severity; however, the detailed mechanism remains unclear. In this study, we investigated mouse models with severe pneumonia caused by SARS-CoV-2 infection by using our in vivo two-photon imaging system. In the lungs of SARS-CoV-2-infected...

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Main Authors: Hiroshi Ueki, I-Hsuan Wang, Maki Kiso, Kenta Horie, Shun Iida, Sohtaro Mine, Michiko Ujie, Hung-Wei Hsu, Chen-Hui Henry Wu, Masaki Imai, Tadaki Suzuki, Wataru Kamitani, Eiryo Kawakami, Yoshihiro Kawaoka
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-55272-0
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https://doi.org/10.1038/s41467-024-55272-0

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