Identification of IGF2BPs-related mRNA signature for predicting the overall survival of lung adenocarcinoma

Identification of IGF2BPs-related mRNA signature for predicting the overall survival of lung adenocarcinoma

Abstract Insulin-like growth factor 2 mRNA-binding proteins (IGF2BPs) are m⁶A readers that stabilize target mRNAs by recognizing the GG(m⁶A)C sequence. While previous studies have explored the biological mechanisms of IGF2BPs in lung cancer, their prognostic value remains unclear. This study investi...

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Bibliographic Details
Main Authors: Xiang Xu, Weidi Zhao, Di Peng, Ying Sun, Jicheng Tantai, Guofang Zhao
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Scientific Reports
Subjects:
M6A
Lung adenocarcinoma
Hypoxia
IL2-STAT5
Prognosis
IGF2BPs
Online Access:https://doi.org/10.1038/s41598-025-87874-z
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