Persistence and emergence of X4 virus in HIV infection
Approximately 50% of late-stage HIV patients develop CXCR4-tropic (X4) virus in addition to CCR5-tropic (R5) virus. X4 emergence occurs with a sharp decline in CD4+ T cell counts and accelerated time to AIDS. Why this phenotypic switch to X4 occurs is not well understood. Previously, we used numeri...
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Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
AIMS Press
2011-03-01
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Series: | Mathematical Biosciences and Engineering |
Subjects: | |
Online Access: | https://www.aimspress.com/article/doi/10.3934/mbe.2011.8.605 |
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