Hyaluronan Synthase 3 Null Mice Exhibit Decreased Intestinal Inflammation and Tissue Damage in the DSS-Induced Colitis Model

Hyaluronan (HA) overproduction is a hallmark of multiple inflammatory diseases, including inflammatory bowel disease (IBD). Hyaluronan can act as a leukocyte recruitment molecule and in the most common mouse model of intestinal inflammation, the chemically induced dextran sodium sulfate (DSS) experi...

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Bibliographic Details
Main Authors: Sean P. Kessler, Dana R. Obery, Carol de la Motte
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:International Journal of Cell Biology
Online Access:http://dx.doi.org/10.1155/2015/745237
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