Evaluation of de novo donor specific antibodies after kidney transplantation in the era of donor-derived cell-free DNA

Evaluation of de novo donor specific antibodies after kidney transplantation in the era of donor-derived cell-free DNA

BackgroundDonor-derived cell-free DNA (dd-cfDNA) is a promising non-invasive biomarker for detecting graft injury in solid organ transplant recipients. Elevated dd-cfDNA levels are strongly associated with rejection and graft injury, especially antibody-mediated rejection (ABMR). While de novo donor...

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Bibliographic Details
Main Authors: Yuan Tian, Lukas Frischknecht, Anna Mallone, Fabian Rössler, Thomas Schachtner, Jakob Nilsson
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Immunology
Subjects:
kidney transplantation
Dd-cfDNA
donor specific antibodies
DSA
mean fluorescence intensity
MFI
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1530065/full
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https://www.frontiersin.org/articles/10.3389/fimmu.2024.1530065/full

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