Metagenome-guided culturomics for the targeted enrichment of gut microbes

Abstract The gut microbiome significantly impacts human health, yet cultivation challenges hinder its exploration. Here, we combine deep whole-metagenome sequencing with culturomics to selectively enrich for taxa and functional capabilities of interest. Using a modified commercial base medium, 50 gr...

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Bibliographic Details
Main Authors: Jeremy Armetta, Simone S. Li, Troels Holger Vaaben, Ruben Vazquez-Uribe, Morten O. A. Sommer
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-55668-y
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