Sex-specific attenuation of constant light-induced memory impairment and Clock gene expression in brain in hepatic Npas2 knockout mice

Sex-specific attenuation of constant light-induced memory impairment and Clock gene expression in brain in hepatic Npas2 knockout mice

Abstract NPAS2 (Neuronal PAS Domain Protein 2) is a component of the core circadian clock and the coordinated activity between central brain and peripheral liver clock proteins postulated to be instrumental for linking behaviour and metabolism. We investigated a conditional liver-specific knockout m...

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Main Authors: Ruby Chrisp, Mitchell Masterson, Rebecca Pope, Christopher J. Roberts, Hilary M. Collins, David J. G. Watson, Derek O’Neil, Kjersti M. Aagaard, Claire L. Gibson, David M. Heery, Paula M. Moran
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-025-92938-1
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https://doi.org/10.1038/s41598-025-92938-1

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