Acute Unilateral Renal Infarction in the Setting of an Inherited Thrombophilia and Atrial Septal Defect

We present a case of renal infarction in a 43-year-old female with history of stroke at age 14. She was found to be heterozygous for the prothrombin G20210A gene mutation. Loop monitoring revealed no atrial fibrillation. Transthoracic and transesophageal echocardiograms showed no thrombus. However,...

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Main Authors: Siavash Piran, Sam Schulman
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:Case Reports in Hematology
Online Access:http://dx.doi.org/10.1155/2017/3159363
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author Siavash Piran
Sam Schulman
author_facet Siavash Piran
Sam Schulman
author_sort Siavash Piran
collection DOAJ
description We present a case of renal infarction in a 43-year-old female with history of stroke at age 14. She was found to be heterozygous for the prothrombin G20210A gene mutation. Loop monitoring revealed no atrial fibrillation. Transthoracic and transesophageal echocardiograms showed no thrombus. However, there was a small shunt due to an atrial septal defect (ASD). She was treated with warfarin and had device closure of her ASD. This was a suspected case of paradoxical embolism through an ASD leading to renal infarction.
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institution Kabale University
issn 2090-6560
2090-6579
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publishDate 2017-01-01
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spelling doaj-art-7aac7310b89c41e280d59f35f55dd20d2025-02-03T07:25:31ZengWileyCase Reports in Hematology2090-65602090-65792017-01-01201710.1155/2017/31593633159363Acute Unilateral Renal Infarction in the Setting of an Inherited Thrombophilia and Atrial Septal DefectSiavash Piran0Sam Schulman1Department of Medicine, Division of Hematology and Thromboembolism and Thrombosis and Atherosclerosis Research Institute, McMaster University, Hamilton, ON, CanadaDepartment of Medicine, Division of Hematology and Thromboembolism and Thrombosis and Atherosclerosis Research Institute, McMaster University, Hamilton, ON, CanadaWe present a case of renal infarction in a 43-year-old female with history of stroke at age 14. She was found to be heterozygous for the prothrombin G20210A gene mutation. Loop monitoring revealed no atrial fibrillation. Transthoracic and transesophageal echocardiograms showed no thrombus. However, there was a small shunt due to an atrial septal defect (ASD). She was treated with warfarin and had device closure of her ASD. This was a suspected case of paradoxical embolism through an ASD leading to renal infarction.http://dx.doi.org/10.1155/2017/3159363
spellingShingle Siavash Piran
Sam Schulman
Acute Unilateral Renal Infarction in the Setting of an Inherited Thrombophilia and Atrial Septal Defect
Case Reports in Hematology
title Acute Unilateral Renal Infarction in the Setting of an Inherited Thrombophilia and Atrial Septal Defect
title_full Acute Unilateral Renal Infarction in the Setting of an Inherited Thrombophilia and Atrial Septal Defect
title_fullStr Acute Unilateral Renal Infarction in the Setting of an Inherited Thrombophilia and Atrial Septal Defect
title_full_unstemmed Acute Unilateral Renal Infarction in the Setting of an Inherited Thrombophilia and Atrial Septal Defect
title_short Acute Unilateral Renal Infarction in the Setting of an Inherited Thrombophilia and Atrial Septal Defect
title_sort acute unilateral renal infarction in the setting of an inherited thrombophilia and atrial septal defect
url http://dx.doi.org/10.1155/2017/3159363
work_keys_str_mv AT siavashpiran acuteunilateralrenalinfarctioninthesettingofaninheritedthrombophiliaandatrialseptaldefect
AT samschulman acuteunilateralrenalinfarctioninthesettingofaninheritedthrombophiliaandatrialseptaldefect