The incidence, mortality, and survival rate of colorectal cancer in Xiamen, China, from 2011 to 2020
Abstract Introduction Currently, nearly one-third of newly diagnosed Colorectal cancer (CRC) cases and associated deaths worldwide are from China. Among Chinese provinces, Fujian exhibited the highest CRC mortality rate. This study aims to analyze long-term trends of CRC epidemiology in Xiamen, Fuji...
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2025-01-01
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| Online Access: | https://doi.org/10.1186/s12889-024-21010-w |
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| author | Lingxian Qiu Wenting Luo Youlan Chen Zhinan Guo Jiali Quan Jiahuang Chi Yingying Guan Yue Huang Yilan Lin |
| author_facet | Lingxian Qiu Wenting Luo Youlan Chen Zhinan Guo Jiali Quan Jiahuang Chi Yingying Guan Yue Huang Yilan Lin |
| author_sort | Lingxian Qiu |
| collection | DOAJ |
| description | Abstract Introduction Currently, nearly one-third of newly diagnosed Colorectal cancer (CRC) cases and associated deaths worldwide are from China. Among Chinese provinces, Fujian exhibited the highest CRC mortality rate. This study aims to analyze long-term trends of CRC epidemiology in Xiamen, Fujian, China. Methods Data were obtained from various cancer surveillance systems, including the Xiamen Cancer Register system, the Xiamen Death Register system, and the household registration system. Trends in incidence, mortality and survival rates from 2011 to 2020 were analyzed using annual percent changes (APC) and average annual percent changes (AAPC), stratified by sex and residency status. Results A total of 7,406 new cases and 3,726 CRC-related deaths were reported from Xiamen. The age-standardized of incidence and mortality rates were 26.09 per 100,000 and 12.70 per 100,000, respectively. The observed 5-year survival rate was 46.65%, with an age-standardized survival of 51.24%. CRC incidence in Xiamen is significantly increasing (AAPC = 4.90%). In contrast, trends in CRC mortality and survival rates are not significant. Urban areas exhibited higher rates of CRC incidence, mortality, and survival rate compared to rural areas, though rural areas showed a more marked upward trend. Conclusions The burden of CRC in Xiamen is notably high, with a concerning increasing in incidence. This underscores the urgent need for targeted strategies to address this public health challenges. |
| format | Article |
| id | doaj-art-7aa7a549596c4739b24f4f31a7a20f84 |
| institution | Kabale University |
| issn | 1471-2458 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Public Health |
| spelling | doaj-art-7aa7a549596c4739b24f4f31a7a20f842025-01-26T12:56:06ZengBMCBMC Public Health1471-24582025-01-012511710.1186/s12889-024-21010-wThe incidence, mortality, and survival rate of colorectal cancer in Xiamen, China, from 2011 to 2020Lingxian Qiu0Wenting Luo1Youlan Chen2Zhinan Guo3Jiali Quan4Jiahuang Chi5Yingying Guan6Yue Huang7Yilan Lin8Xiamen Center for Disease Control and PreventionDepartment of Research, The First Affiliated Hospital of Xiamen UniversityXiamen Center for Disease Control and PreventionXiamen Center for Disease Control and PreventionState Key Laboratory of Vaccines for Infectious Diseases, Xiang An Biomedicine Laboratory, School of Public Health, Xiamen UniversityXiamen Center for Disease Control and PreventionZhongshan Hospital, Fudan University (Xiamen Branch)State Key Laboratory of Vaccines for Infectious Diseases, Xiang An Biomedicine Laboratory, School of Public Health, Xiamen UniversityXiamen Center for Disease Control and PreventionAbstract Introduction Currently, nearly one-third of newly diagnosed Colorectal cancer (CRC) cases and associated deaths worldwide are from China. Among Chinese provinces, Fujian exhibited the highest CRC mortality rate. This study aims to analyze long-term trends of CRC epidemiology in Xiamen, Fujian, China. Methods Data were obtained from various cancer surveillance systems, including the Xiamen Cancer Register system, the Xiamen Death Register system, and the household registration system. Trends in incidence, mortality and survival rates from 2011 to 2020 were analyzed using annual percent changes (APC) and average annual percent changes (AAPC), stratified by sex and residency status. Results A total of 7,406 new cases and 3,726 CRC-related deaths were reported from Xiamen. The age-standardized of incidence and mortality rates were 26.09 per 100,000 and 12.70 per 100,000, respectively. The observed 5-year survival rate was 46.65%, with an age-standardized survival of 51.24%. CRC incidence in Xiamen is significantly increasing (AAPC = 4.90%). In contrast, trends in CRC mortality and survival rates are not significant. Urban areas exhibited higher rates of CRC incidence, mortality, and survival rate compared to rural areas, though rural areas showed a more marked upward trend. Conclusions The burden of CRC in Xiamen is notably high, with a concerning increasing in incidence. This underscores the urgent need for targeted strategies to address this public health challenges.https://doi.org/10.1186/s12889-024-21010-wColorectal cancerIncidenceMortalitySurvival rateTrend |
| spellingShingle | Lingxian Qiu Wenting Luo Youlan Chen Zhinan Guo Jiali Quan Jiahuang Chi Yingying Guan Yue Huang Yilan Lin The incidence, mortality, and survival rate of colorectal cancer in Xiamen, China, from 2011 to 2020 BMC Public Health Colorectal cancer Incidence Mortality Survival rate Trend |
| title | The incidence, mortality, and survival rate of colorectal cancer in Xiamen, China, from 2011 to 2020 |
| title_full | The incidence, mortality, and survival rate of colorectal cancer in Xiamen, China, from 2011 to 2020 |
| title_fullStr | The incidence, mortality, and survival rate of colorectal cancer in Xiamen, China, from 2011 to 2020 |
| title_full_unstemmed | The incidence, mortality, and survival rate of colorectal cancer in Xiamen, China, from 2011 to 2020 |
| title_short | The incidence, mortality, and survival rate of colorectal cancer in Xiamen, China, from 2011 to 2020 |
| title_sort | incidence mortality and survival rate of colorectal cancer in xiamen china from 2011 to 2020 |
| topic | Colorectal cancer Incidence Mortality Survival rate Trend |
| url | https://doi.org/10.1186/s12889-024-21010-w |
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