Carotid baroreceptor stimulation attenuates obesity-related hypertension through sympathetic-driven IL- 22 restoration of intestinal homeostasis

Carotid baroreceptor stimulation attenuates obesity-related hypertension through sympathetic-driven IL- 22 restoration of intestinal homeostasis

Abstract Background Gut microbiota and its metabolites, as well as the intestinal barrier, play important roles in the development of obesity-related hypertension. Sympathetic nerves are critical for intestinal homeostasis. Carotid baroreceptor stimulation (CBS) has been shown to exert protective ef...

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Main Authors: Ling Shu, Lingling Xiao, Bangwang Hu, Qiao Yu, Dilin Dai, Jie Chen, Jing Wang, Zhaoqing Xi, Junxia Zhang, Mingwei Bao
Format: Article
Language:English
Published: BMC 2025-04-01
Series:European Journal of Medical Research
Subjects:
Obesity-related hypertension
Sympathetic nerve
Gut microbiota
Intestinal barrier
Interleukin- 22
Online Access:https://doi.org/10.1186/s40001-025-02528-0
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https://doi.org/10.1186/s40001-025-02528-0

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