甘草甜素预防二乙基亚硝胺致大鼠肝癌作用的剂量-效应关系

应用二乙基亚硝胺(DEN)致大鼠肝癌作用短期体内实验模型,对甘草甜素的抑癌作用进行了量效关系研究。结果发现最低有效剂量为216.2mg/kg,最佳效应剂量为432.4mg/kg,而剂量为864.8mg/kg时,虽有预防作用,效果较432.4mg/kg弱(P<0.1);108.1mg/kg,216.2mg/kg和432.4mg/kg显示了量效关系。...

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Bibliographic Details
Format: Article
Language:zho
Published: Editorial Office of Journal of Sun Yat-sen University 1994-01-01
Series:Zhongshan Daxue xuebao. Yixue kexue ban
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Online Access:http://xuebaoyx.sysu.edu.cn/zh/article/43590933/
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