Highly Aggressive Intraparenchymal Solitary Fibrous Tumor of the Lung with Distant Metastasis: A Case Report and Review of CT and PET/CT Findings
<b>Background and Clinical Significance:</b> Solitary fibrous tumors (SFTs) arising from the lung parenchyma without any relation to the pleura are rare. <b>Case Presentation:</b> We report a case of highly aggressive intraparenchymal SFT of the lung in a 52-year-old woman wi...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2025-05-01
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| Series: | Reports |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2571-841X/8/2/78 |
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| Summary: | <b>Background and Clinical Significance:</b> Solitary fibrous tumors (SFTs) arising from the lung parenchyma without any relation to the pleura are rare. <b>Case Presentation:</b> We report a case of highly aggressive intraparenchymal SFT of the lung in a 52-year-old woman with rapid distant metastasis to the brain, lungs, and bones within one year post-operation. Chest computed tomography (CT) showed a 5.5 cm-sized, round, but partially lobulated mass with ambiguous enhancement in the right upper lobe. Positron emission tomography/computed tomography (PET/CT) demonstrated strong homogeneous FDG uptake. Unfortunately, the patient succumbed to the disease within one year of diagnosis. <b>Conclusions:</b> Among intrapulmonary SFT, the cellular variant may appear as a cystic mass due to accompanying hemorrhage, coagulation necrosis, and myxoid degeneration. In the absence of mediastinal metastatic adenopathy, it can be mistaken for a benign cystic mass, making PET/CT findings a crucial tool for suggesting a malignancy. Furthermore, as cellular-type intrapulmonary SFT can exhibit aggressive distant metastasis, understanding the CT and PET/CT findings in this condition is essential for accurate diagnosis and treatment planning. |
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| ISSN: | 2571-841X |