Transcriptome analysis of novel B16 melanoma metastatic variants generated by serial intracarotid artery injection

Abstract The incidence of brain metastases (BrM) in patients with metastatic melanoma is reported to be 30–50% and constitutes the third most frequent BrM after breast and renal cancers. Treatment strategies including surgical resection, stereotactic radiation, and immunotherapy have improved clinic...

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Bibliographic Details
Main Authors: Jenny C. Kienzler, Erick M. Contreras, Janet Treger, Linda M. Liau, Geoffrey C. Owens, Robert M. Prins
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Acta Neuropathologica Communications
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Online Access:https://doi.org/10.1186/s40478-025-01924-1
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