H3K27me3-mediated epigenetic regulation of TET1 in the eutopic endometrium of women with endometriosis and infertility

H3K27me3-mediated epigenetic regulation of TET1 in the eutopic endometrium of women with endometriosis and infertility

Abstract Endometriosis is a common gynecological condition associated with chronic inflammation, epigenetic dysregulation, and infertility. The TET1 gene, involved in DNA demethylation, may be regulated by repressive histone modifications such as H3K27me3, but its role in endometriosis remains poorl...

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Main Authors: Magdalena Adamczyk, Agnieszka Rawłuszko-Wieczorek, Przemysław Wirstlein, Marta Nowacka, Michał Nowicki, Paweł Piotr Jagodziński, Ewa Wender-Ożegowska, Małgorzata Kędzia
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Scientific Reports
Subjects:
Endometriosis
Eutopic endometrium
Histone modification
H3K27me3
Infertility
TET protein
Online Access:https://doi.org/10.1038/s41598-025-13618-8
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https://doi.org/10.1038/s41598-025-13618-8

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