Lung-specific CRBN knockout attenuates influenza a virus-induced acute lung injury in mice: a potential therapeutic approach

Abstract Influenza-related acute lung injury is a life-threatening condition primarily caused by uncontrolled replication of the influenza virus and intense proinflammatory responses. Cereblon (CRBN) is a protein known for its role in the ubiquitin-proteasome system and as a target of the drug thali...

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Bibliographic Details
Main Authors: Lifang Zhang, Qingchao Zhang, Jiahui Chang, Yunyi Zhou, Wei Wang, Xiliang Wang, Chengyu Jiang, Yanli Zhang
Format: Article
Language:English
Published: BMC 2025-01-01
Series:BMC Infectious Diseases
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Online Access:https://doi.org/10.1186/s12879-025-10490-9
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