Crosstalk between metabolism and epigenetics during macrophage polarization

Abstract Macrophage polarization is a dynamic process driven by a complex interplay of cytokine signaling, metabolism, and epigenetic modifications mediated by pathogens. Upon encountering specific environmental cues, monocytes differentiate into macrophages, adopting either a pro-inflammatory (M1)...

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Bibliographic Details
Main Authors: Kangling Zhang, Chinnaswamy Jagannath
Format: Article
Language:English
Published: BMC 2025-03-01
Series:Epigenetics & Chromatin
Subjects:
Online Access:https://doi.org/10.1186/s13072-025-00575-9
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