Storage Artifact Masquerading as Yeast: Presenting a Diagnostic Pitfall
Abnormal cell morphology can result from prolonged specimen storage, both for red and white blood cells. In particular, nuclear pyknosis of segmented neutrophils can occur in both peripheral blood and body fluids and may represent a diagnostic pitfall as it can mimic intracellular yeast or bacteria...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2022-01-01
|
| Series: | Case Reports in Pathology |
| Online Access: | http://dx.doi.org/10.1155/2022/3326214 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832561646061486080 |
|---|---|
| author | Elena M. Fenu Tawfeq Naal Elizabeth Palavecino |
| author_facet | Elena M. Fenu Tawfeq Naal Elizabeth Palavecino |
| author_sort | Elena M. Fenu |
| collection | DOAJ |
| description | Abnormal cell morphology can result from prolonged specimen storage, both for red and white blood cells. In particular, nuclear pyknosis of segmented neutrophils can occur in both peripheral blood and body fluids and may represent a diagnostic pitfall as it can mimic intracellular yeast or bacteria morphology. Pathologists are frequently asked to examine body fluid smears which are thought to contain microorganisms, and the presence of an unexpected organism can be especially concerning. Morphologic changes from prolonged storage may be encountered infrequently, and it is important to be aware of them in order to avoid misrepresentation, as additional work-up may be required for a suspected case of an unexpected fungal infection. |
| format | Article |
| id | doaj-art-796d8e1722fe44b39eda1d2e06922aa3 |
| institution | Kabale University |
| issn | 2090-679X |
| language | English |
| publishDate | 2022-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Pathology |
| spelling | doaj-art-796d8e1722fe44b39eda1d2e06922aa32025-02-03T01:24:29ZengWileyCase Reports in Pathology2090-679X2022-01-01202210.1155/2022/3326214Storage Artifact Masquerading as Yeast: Presenting a Diagnostic PitfallElena M. Fenu0Tawfeq Naal1Elizabeth Palavecino2Department of PathologyDepartment of PathologyDepartment of PathologyAbnormal cell morphology can result from prolonged specimen storage, both for red and white blood cells. In particular, nuclear pyknosis of segmented neutrophils can occur in both peripheral blood and body fluids and may represent a diagnostic pitfall as it can mimic intracellular yeast or bacteria morphology. Pathologists are frequently asked to examine body fluid smears which are thought to contain microorganisms, and the presence of an unexpected organism can be especially concerning. Morphologic changes from prolonged storage may be encountered infrequently, and it is important to be aware of them in order to avoid misrepresentation, as additional work-up may be required for a suspected case of an unexpected fungal infection.http://dx.doi.org/10.1155/2022/3326214 |
| spellingShingle | Elena M. Fenu Tawfeq Naal Elizabeth Palavecino Storage Artifact Masquerading as Yeast: Presenting a Diagnostic Pitfall Case Reports in Pathology |
| title | Storage Artifact Masquerading as Yeast: Presenting a Diagnostic Pitfall |
| title_full | Storage Artifact Masquerading as Yeast: Presenting a Diagnostic Pitfall |
| title_fullStr | Storage Artifact Masquerading as Yeast: Presenting a Diagnostic Pitfall |
| title_full_unstemmed | Storage Artifact Masquerading as Yeast: Presenting a Diagnostic Pitfall |
| title_short | Storage Artifact Masquerading as Yeast: Presenting a Diagnostic Pitfall |
| title_sort | storage artifact masquerading as yeast presenting a diagnostic pitfall |
| url | http://dx.doi.org/10.1155/2022/3326214 |
| work_keys_str_mv | AT elenamfenu storageartifactmasqueradingasyeastpresentingadiagnosticpitfall AT tawfeqnaal storageartifactmasqueradingasyeastpresentingadiagnosticpitfall AT elizabethpalavecino storageartifactmasqueradingasyeastpresentingadiagnosticpitfall |