Antidepressant-like effect of picralima nitida total crude alkaloidal fraction in mice

Antidepressant-like effect of picralima nitida total crude alkaloidal fraction in mice

In 2019, WHO, reported that an estimate of 350 million people globally have depression. Despite the advances made in current pharmacotherapy, about 30–40 % of patients receive insufficient treatment because of the increased occurrence of partial or non-response as well as delayed onset of antidepres...

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Bibliographic Details
Main Authors: Prince Dagadu Okyere, Christian Chukwuma Ndu, Donatus Wewura Adongo, Charles Kwaku Benneh, Eric Woode, Edmund Ekuadzi, Wonder Kofi Mensah Abotsi, Eric Boakye-Gyasi, Priscilla Kolibea Mante
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Scientific African
Subjects:
Depression
Tail suspension test
Forced swim test
Tail noradrenergic pathway
5-hydroxytryptamine
Reserpine
Online Access:http://www.sciencedirect.com/science/article/pii/S2468227625000195
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