In silico design of a multi-epitope vaccine against Mycobacterium avium subspecies paratuberculosis

In silico design of a multi-epitope vaccine against Mycobacterium avium subspecies paratuberculosis

The widespread chronic enteritis known as Paratuberculosis (PTB) or Johne's disease (JD) is caused by Mycobacterium avium subspecies paratuberculosis (MAP), posing a significant threat to global public health. Given the challenges associated with PTB or JD, the development and application of va...

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Bibliographic Details
Main Authors: Weiqi Guo, Xinyu Wang, Jiangang Hu, Beibei Zhang, Luru Zhao, Guangdong Zhang, Jingjing Qi, Zuzhang Wei, Yanqing Bao, Mingxing Tian, Shaohui Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Immunology
Subjects:
multi-epitope vaccine
Mycobacterium avium subspecies paratuberculosis
pan-genome
reverse vaccinology
molecular dynamics
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1505313/full
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https://www.frontiersin.org/articles/10.3389/fimmu.2025.1505313/full

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