Study of the Boson Peak and Fragility of Bioprotectant Glass-Forming Mixtures by Neutron Scattering
The biological relevance of trehalose, glycerol, and their mixtures in several anhydrobiotic and cryobiotic organisms has recently promoted both experimental and simulation studies. In addition, these systems are employed in different industrial fields, such as pharmaceutical and cosmetic industries...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | Advances in Materials Science and Engineering |
| Online Access: | http://dx.doi.org/10.1155/2013/128271 |
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| author | F. Migliardo S. Magazù M. A. Gonzalez C. Mondelli |
| author_facet | F. Migliardo S. Magazù M. A. Gonzalez C. Mondelli |
| author_sort | F. Migliardo |
| collection | DOAJ |
| description | The biological relevance of trehalose, glycerol, and their mixtures in several anhydrobiotic and cryobiotic organisms has recently promoted both experimental and simulation studies. In addition, these systems are employed in different industrial fields, such as pharmaceutical and cosmetic industries, as additives in mixtures for cryopreservation and in several formulations. This review article shows an overview of Inelastic Neutron Scattering (INS) data, collected at different temperature values by the OSIRIS time-of-flight spectrometer at the ISIS Facility (Rutherford Appleton Laboratory, Oxford, UK) and by the IN4 and IN6 spectrometers at the Institut Laue Langevin (ILL, Grenoble, France), on trehalose/glycerol mixtures as a function of the glycerol content. The data analysis allows determining the Boson peak behavior and discussing the findings in terms of fragility in relation to the bioprotective action of trehalose and glycerol. |
| format | Article |
| id | doaj-art-78f1e9242195494dad9c3669ddf65ed8 |
| institution | Kabale University |
| issn | 1687-8434 1687-8442 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Advances in Materials Science and Engineering |
| spelling | doaj-art-78f1e9242195494dad9c3669ddf65ed82025-02-03T01:09:50ZengWileyAdvances in Materials Science and Engineering1687-84341687-84422013-01-01201310.1155/2013/128271128271Study of the Boson Peak and Fragility of Bioprotectant Glass-Forming Mixtures by Neutron ScatteringF. Migliardo0S. Magazù1M. A. Gonzalez2C. Mondelli3Department of Physics and Earth Sciences, University of Messina, Viale D’Alcontres 31, P.O. Box 55, 98166 Messina, ItalyDepartment of Physics and Earth Sciences, University of Messina, Viale D’Alcontres 31, P.O. Box 55, 98166 Messina, ItalyInstitut Laue Langevin, 6 rue Jules Horowitz, 38042 Grenoble Cedex 9, FranceCNR-IOM-OGG, Institut Laue Langevin, 6 rue Jules Horowitz, 38042 Grenoble Cedex 9, FranceThe biological relevance of trehalose, glycerol, and their mixtures in several anhydrobiotic and cryobiotic organisms has recently promoted both experimental and simulation studies. In addition, these systems are employed in different industrial fields, such as pharmaceutical and cosmetic industries, as additives in mixtures for cryopreservation and in several formulations. This review article shows an overview of Inelastic Neutron Scattering (INS) data, collected at different temperature values by the OSIRIS time-of-flight spectrometer at the ISIS Facility (Rutherford Appleton Laboratory, Oxford, UK) and by the IN4 and IN6 spectrometers at the Institut Laue Langevin (ILL, Grenoble, France), on trehalose/glycerol mixtures as a function of the glycerol content. The data analysis allows determining the Boson peak behavior and discussing the findings in terms of fragility in relation to the bioprotective action of trehalose and glycerol.http://dx.doi.org/10.1155/2013/128271 |
| spellingShingle | F. Migliardo S. Magazù M. A. Gonzalez C. Mondelli Study of the Boson Peak and Fragility of Bioprotectant Glass-Forming Mixtures by Neutron Scattering Advances in Materials Science and Engineering |
| title | Study of the Boson Peak and Fragility of Bioprotectant Glass-Forming Mixtures by Neutron Scattering |
| title_full | Study of the Boson Peak and Fragility of Bioprotectant Glass-Forming Mixtures by Neutron Scattering |
| title_fullStr | Study of the Boson Peak and Fragility of Bioprotectant Glass-Forming Mixtures by Neutron Scattering |
| title_full_unstemmed | Study of the Boson Peak and Fragility of Bioprotectant Glass-Forming Mixtures by Neutron Scattering |
| title_short | Study of the Boson Peak and Fragility of Bioprotectant Glass-Forming Mixtures by Neutron Scattering |
| title_sort | study of the boson peak and fragility of bioprotectant glass forming mixtures by neutron scattering |
| url | http://dx.doi.org/10.1155/2013/128271 |
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