Lactate inhibits mouse embryonic palatal mesenchyme cells chondrogenesis through AKT-PKM2 axis

Abstract Background The development of the palate is a complex and continuous process, occurring in a series of stages with cartilage of being particular significance. Chondrogenesis is influenced by many factors such as metabolism, and hypoxia which are also risk factors for cleft palate. Hypoxia c...

Full description

Saved in:
Bibliographic Details
Main Authors: Mingyue Meng, Xige Zhao, Xiaoyu Zheng, Xiaotong Wang, Xia Peng, Zhiwei Wang, Shiteng Wang, Cui Guo, Juan Du
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Oral Health
Subjects:
Online Access:https://doi.org/10.1186/s12903-025-06632-9
Tags: Add Tag
No Tags, Be the first to tag this record!