SPARC Promotes Aerobic Glycolysis and 5‐Fluorouracil Resistance in Colorectal Cancer Through the STAT3/HK2 Axis

ABSTRACT Background Chemotherapy has been used extensively in the clinic to treat colorectal cancer (CRC). Nevertheless, cancer cells usually develop chemoresistance under chemotherapy stress, leading to treatment failure. At present, the mechanism of chemoresistance in patients with CRC is not full...

Full description

Saved in:
Bibliographic Details
Main Authors: Jingrong Xiang, Huan Zhang, Kanger Shen, Jie Feng, Kexi Yang, Tongguo Shi, Qinhua Xi
Format: Article
Language:English
Published: Wiley 2025-06-01
Series:Cancer Medicine
Subjects:
Online Access:https://doi.org/10.1002/cam4.70972
Tags: Add Tag
No Tags, Be the first to tag this record!