Adenoviral Vector-Based Vaccine Expressing Hemagglutinin Stem Region with Autophagy-Inducing Peptide Confers Cross-Protection Against Group 1 and 2 Influenza A Viruses

Adenoviral Vector-Based Vaccine Expressing Hemagglutinin Stem Region with Autophagy-Inducing Peptide Confers Cross-Protection Against Group 1 and 2 Influenza A Viruses

<b>Background/Objectives:</b> An effective universal influenza vaccine is urgently needed to overcome the limitations of current seasonal influenza vaccines, which are ineffective against mismatched strains and unable to protect against pandemic influenza. <b>Methods:</b> In...

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Bibliographic Details
Main Authors: Wen-Chien Wang, Ekramy E. Sayedahmed, Marwa Alhashimi, Ahmed Elkashif, Vivek Gairola, Muralimanohara S. T. Murala, Suryaprakash Sambhara, Suresh K. Mittal
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Vaccines
Subjects:
human adenoviral vector
bovine adenoviral vector
nonhuman adenoviral vector
adenoviral vector
hemagglutinin stem
extracellular domain of matrix protein 2
Online Access:https://www.mdpi.com/2076-393X/13/1/95
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